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8.7 – Stem cells in the skin: visible aging and regenerative capacity

8.7 – Células madre en la piel: envejecimiento visible y capacidad regenerativa

The skin is the organ that most clearly reflects the passage of time. But behind the wrinkles, sagging, or loss of radiance, there is a silent process: the progressive depletion of epidermal and dermal stem cells , responsible for regenerating the different layers of the skin and maintaining its structure, elasticity, and barrier function.

These skin stem cells reside primarily in the basal layer of the epidermis and the follicular zone. They are responsible for replacing dead cells, healing wounds, producing new collagen fibers, and maintaining deep hydration. However, oxidative stress, UV radiation, chronic inflammation, and nutritional deficiencies cause these cells to lose their ability to renew themselves over time.


Signs that skin stem cells are in decline

  • Loss of skin thickness and tendency to dryness.

  • Fine wrinkles that progress in depth.

  • Dull tone and uneven pigmentation.

  • Slow healing or alterations in regeneration after injuries.

  • Increased sensitivity or appearance of microinflammation.

When the dermal microenvironment becomes inflamed or acidic and oxidative, stem cells stop dividing properly, disrupting the skin renewal cycle .


Sevens products that help protect and revitalize skin stem cells

Biotin Sevens

A key vitamin for maintaining healthy skin, hair, and mucous membranes. It participates in gene expression in skin cells and stimulates keratinocyte regeneration.

Sevens Multivitamins

Contains vitamins A, C, D, E, zinc and selenium, all of which are essential for collagen synthesis, antioxidant protection and skin metabolism.

Organic Turmeric Sevens

Systemic anti-inflammatory that modulates the cutaneous environment , reduces oxidative microstress and promotes the expression of genes associated with dermal cellular longevity.

Astaxanthin Sevens

It protects against UV radiation, prevents collagen degradation, and improves skin elasticity and firmness . Its mitochondrial antioxidant action is key to preserving the dermal stem cell niche.

Omega 3 Sevens (fish oil)

It helps maintain skin hydration from within, modulates subclinical chronic inflammation, and protects skin cell membranes.

D3 + K2 Sevens

Vitamin D regulates dermal immunity, supports cell differentiation and accelerates wound healing , while K2 contributes to maintaining subcutaneous vascular integrity.


Essential habits to preserve the youthfulness of skin cells

  • Protect yourself from the sun with physical barriers or natural filters.

  • Avoid tobacco, alcohol, and excess sugar, all of which are collagen-damaging.

  • Maintain good hydration and night rest.

  • Prioritize a diet rich in antioxidants and healthy fats.


Conclusion

Skin ages because its ability to renew itself decreases, and this directly depends on the vitality of its stem cells. Through a comprehensive approach like the one proposed by Sevens—focused on cellular nutrition, reducing oxidative stress, and modulating the dermal environment—it is possible to restore the skin's natural regenerative function, slowing visible aging from within .