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8.6 – How sleep and circadian rhythms affect stem cell renewal

8.6 – Cómo el sueño y los ritmos circadianos afectan la renovación de células madre

Getting a good night's sleep doesn't just improve concentration or mood. While we sleep, the body activates profound processes of cellular repair, cleansing, and renewal , and this includes the activity of our stem cells . These key regenerative cells rely on hormonal and metabolic signals that follow a circadian rhythm —a 24-hour cycle regulated primarily by light, darkness, and rest.

When this rhythm is disrupted—due to insomnia, jet lag, night shift work, or nighttime exposure to screens—stem cells lose effectiveness, their capacity for division and regeneration decreases, and their niche becomes more inflamed. Consequently, tissue aging accelerates and recovery from exercise or illness is compromised.


Scientific evidence: sleep as a regulator of rejuvenation

  • During deep sleep, mitophagy is activated, a key process for removing damaged mitochondria from stem cells.

  • The production of melatonin , the sleep hormone, has a direct protective effect on DNA and stem cell niches.

  • The brain's glymphatic system is only activated during deep sleep, clearing molecular debris that affects neural stem cells.

  • Chronic sleep deprivation increases cortisol and inflammation, inhibiting tissue regeneration.


Sevens products that optimize rest and protect nighttime regenerative function

Melatonin Sevens

It induces physiological sleep, regulates internal biological clocks, and activates longevity genes such as SIRT1. It stimulates nocturnal autophagy and protects stem cell niches.

Magnesium Sevens

It improves sleep quality by regulating neuromuscular relaxation and parasympathetic nervous system activity. It is key to natural melatonin synthesis and HPA axis balance.

Curcumin C3 Reduce Sevens

It reduces nocturnal inflammation, regulates metabolic pathways associated with sleep, and protects cellular niches from inflammatory signals that interfere with restful sleep.

Sevens Multivitamins

It provides vitamin B6 (a precursor to serotonin and melatonin), B12 (synchronizes circadian clocks), and magnesium, all necessary for nocturnal hormone synthesis and cellular recovery.

Omega 3 Sevens (fish oil)

It improves brain plasticity and reduces anxiety or mild insomnia associated with inflammation , promoting a smoother transition to deep sleep.


Key habits to protect your circadian rhythm and stem cells

  • Sleep between 7 and 9 hours each night, regularly.

  • Avoid bright screens and cold lights after sunset.

  • Expose yourself to natural light upon waking and maintain consistent schedules.

  • Eat dinner early and light so as not to interfere with nocturnal regenerative signaling.

  • Avoid caffeine, alcohol, and heavy meals at night.


Conclusion

Getting a good night's sleep isn't a luxury: it's a biological necessity. During sleep, the machinery that cleanses, repairs, and regenerates our bodies is activated, and stem cells are at the center of this process. With the support of the Sevens strategy—focused on deep sleep, reducing nighttime inflammation, and mitochondrial support—you can turn every night into a real opportunity for root-level cellular rejuvenation.