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8.5 – Factors that damage stem cells: inflammation, toxins, and oxidative stress

8.5 – Factores que dañan las células madre: inflamación, tóxicos y estrés oxidativo

Stem cells are extraordinary in their ability to renew and differentiate, but they are also vulnerable. Their environment—known as their "niche"—must be kept clean, protected, and well-nourished so that these cells can perform their regenerative function. When exposed to chronic inflammation, oxidative stress, or environmental toxins , their number and functionality decline dramatically.

These factors not only damage them directly, but also alter the biochemical signals that allow their activation, division, or differentiation . As a result, the body loses its ability to regenerate, adapt to stress, and respond to injury or disease.


The main aggressors of stem cells

  • Low-grade systemic inflammation ( inflammaging ), which alters regenerative niches.

  • Free radicals that damage DNA, proteins and cell membranes.

  • Heavy metals and hormone disruptors that accumulate in tissues.

  • Mitochondrial dysfunction , which generates proinflammatory cellular environments.

  • Excess glucose, alcohol, tobacco or chronic drugs , which negatively impact regenerative tissues.


Sevens strategy to protect stem cells from chronic damage

Astaxanthin Sevens

A highly potent lipophilic antioxidant, it accumulates in cell membranes and protects stem cell DNA from mitochondrial and oxidative damage. It also reduces systemic inflammation.

Curcumin C3 Reduce Sevens

It modulates inflammatory pathways (such as NF-κB), stimulates autophagy, and helps eliminate intracellular waste. It preserves regenerative signaling in cellular niches.

Detox Sevens

Formulation focused on supporting the liver's elimination of accumulated toxins , including heavy metals and inflammatory metabolites. Promotes a cleaner environment for stem cells.

Omega 3 Sevens (fish oil)

It inhibits the production of inflammatory cytokines, preserves the integrity of cell membranes and improves the metabolic sensitivity of tissues.

Sevens Multivitamins

It provides antioxidants such as vitamins C and E, as well as selenium and zinc, essential cofactors for protection against oxidative stress and the maintenance of cellular repair machinery.

Melatonin Sevens

It regulates nighttime inflammation, stimulates the clearance of molecular waste, and activates cellular longevity pathways such as SIRT1 and mitophagy. Ideal for supporting nighttime cleansing and repair processes.

Magnesium Sevens

Essential for cellular antioxidant enzymes, it stabilizes DNA, regulates immune response, and protects against damage induced by chronic inflammation or environmental toxicity.


Practical recommendations to reduce stem cell aggressors:

  • Avoid excessive consumption of ultra-processed foods, alcohol, and refined sugars.

  • Sleep 7–8 hours each night, respecting circadian rhythms.

  • Maintain optimal hydration and promote sweating (physical activity or sauna).

  • Practice short fasts or eating in time windows.

  • Minimize exposure to unnecessary household pollutants and industrial chemicals.


Conclusion

It's not enough to simply "activate" stem cells if their environment is damaged. Protecting their niche is the first step to keeping them young, functional, and available when the body needs them. Sevens' strategy—focused on antioxidation, detoxification, inflammation control, and mitochondrial support—offers an effective and sustainable approach to preserving regenerative health from the cellular foundation.