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9.5 – The role of microbiota in cell signaling: the gut-brain-immunity axis

9.5 – El papel de la microbiota en la señalización celular: el eje intestino-cerebro-inmunidad

More than 100 trillion microorganisms live in the gut, making up the intestinal microbiota . Far from being simple "hosts," these commensal bacteria are an active part of our biology: they produce neurotransmitters, regulate inflammation, modulate immunity, and participate in nutrient absorption and synthesis . In fact, the gut has earned the title of "second brain" due to its density of neurons and its ability to communicate with the entire body.

Through the gut-brain-immune axis , the microbiota interacts with the central nervous system, the immune system, and the endocrine system. When this intestinal flora becomes unbalanced (dysbiosis), cellular dialogue between organs becomes distorted, leading to symptoms such as brain fog, anxiety, fatigue, allergies, chronic inflammation, and digestive disorders.


How does communication break down when there is dysbiosis?

  • Harmful bacteria produce toxins that disrupt the function of cell receptors.

  • Intestinal permeability (“leaky gut”) increases, exposing the immune system to unrecognized molecules.

  • The production of GABA, serotonin, dopamine and other neurotransmitters is reduced.

  • The metabolism of B vitamins, which are necessary for methylation and cell signaling, is altered.

  • It increases local and systemic inflammation, blocking regeneration and repair pathways.

An altered microbiota directly interferes with intracellular, immunological and neurological communication , affecting our capacity to respond and adapt.


Sevens products that help restore the microbiota and the intestinal signaling axis

Biotin Sevens

It contributes to the maintenance of mucous membranes and promotes the regeneration of the intestinal epithelium , protecting the intestinal barrier and influencing immune regulation.

Organic Turmeric Sevens

It acts as a mild prebiotic, modulates intestinal inflammation and promotes bacterial diversity , favoring a more balanced microbiota.

Sevens Multivitamins

It provides vitamins B1, B6, B9 and B12, essential for neuronal function and the synthesis of neurotransmitters produced or modulated by the microbiota.

Detox Sevens

Supports liver function in the elimination of bacterial endotoxins and reduces intestinal toxic load , facilitating a healthier environment for commensal flora.

Omega 3 Sevens (fish oil)

It modulates intestinal inflammation, promotes epithelial integrity, and improves mucosal immune signaling.

Magnesium Sevens

It regulates intestinal transit, intervenes in neuromuscular communication in the digestive tract, and supports the production of GABA and intestinal serotonin.


Habits to improve the gut-brain-immune axis

  • Include natural fermented foods (kefir, sauerkraut, kombucha).

  • Increase prebiotic fiber (garlic, onion, green banana, asparagus).

  • Reduce refined sugar, alcohol, and ultra-processed foods.

  • Get a good night's sleep and reduce stress, as cortisol unbalances your gut flora.

  • Eat slowly, chew well, and do not eat while anxious.


Conclusion

The gut doesn't just digest: it thinks, regulates, and communicates. A healthy microbiota is a necessary condition for maintaining functional cellular communication throughout the body. With Sevens' holistic approach—focused on regenerating the intestinal barrier, modulating inflammation, and nourishing the nervous system and immunity—we can restore the gut-brain axis and regain biological synchrony from the root.