In recent years, scientists have identified a special class of compounds called senolytics : substances capable of inducing the selective death of senescent cells , without affecting healthy cells. This strategy not only reduces SASP and systemic inflammation, but also restores tissue function and improves longevity indicators in animal models.
Some senolytics are undergoing pharmacological studies, but many are found in nature, in foods or supplements, with growing evidence. Including these nutrients regularly can be key to supporting the body's natural processes of cellular cleansing and tissue rejuvenation .
Nutrients with documented senolytic or senotherapeutic activity
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Curcumin : induces autophagy, inhibits NF-κB, reduces the expression of survival genes in senescent cells.
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Astaxanthin : Powerful mitochondrial action that weakens senescent cells and strengthens healthy ones.
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Omega 3 (EPA/DHA) : modulate anti-inflammatory pathways and promote a cellular environment unfavorable to senescence.
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Quercetin and fisetin (not directly present in Sevens, but share effects with other polyphenols).
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Melatonin : stimulates nocturnal autophagy and modulates genes involved in cellular longevity.
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Vitamins and minerals : Many vitamin cofactors (C, D, B12, zinc, selenium) enhance the natural senolytic effects by improving immunity, detoxification and cellular integrity.
Sevens products with senolytic or senescence-modulating effects
Curcumin C3 Reduce Sevens
One of the most studied natural senolytics. It induces autophagy, promotes the elimination of damaged proteins, and reduces the survival of senescent cells in in vitro and in vivo models.
Astaxanthin Sevens
It acts as a selective modulator of mitochondrial oxidative stress. It weakens the viability of senescent cells while strengthening the antioxidant protection of young cells .
Omega 3 Sevens (fish oil)
Reprograms the epigenetic and inflammatory environment. Studies have shown that omega-3s limit the expansion of senescent cells in metabolic and cardiovascular tissues.
Melatonin Sevens
It supports cellular cleansing during sleep. It stimulates the activity of genes linked to longevity (such as SIRT1) and promotes the physiological elimination of aged cells.
Detox Sevens
Supports the hepatic elimination of waste products released during the death of senescent cells. Essential in cell renewal or fasting protocols.
Sevens Multivitamins
Provides cofactors that amplify the senolytic effects of other compounds: zinc, selenium, vitamin C, D, B6, B12, folic acid.
Creatine Sevens
It improves cellular bioenergetics, limiting the metabolic environment that promotes senescence. It supports tissue recovery after senolytic clearance.
D3 + K2 Sevens
Vitamin D enhances natural immunosurveillance, helping to detect senescent cells, while K2 protects tissues from calcification associated with aging.
Conclusion
Eliminating senescent cells is possible. Nature provides us with effective and well-tolerated tools that, combined with habits like fasting, exercise, and stress management, can transform cellular biology and rejuvenate tissues from within . Sevens offers a comprehensive selection of supplements with senolytic and protective properties, designed to work synergistically to help you restore your cellular health with precision and science .