DNA Methylation: Epigenetic Key to Cancer Prevention and Treatment
DNA methylation is one of the most researched epigenetic mechanisms currently, especially due to its role in the development of cancer. This chemical process, which involves the addition of methyl groups to certain regions of DNA, acts as a switch that regulates gene expression without altering their sequence. Its proper functioning is vital for maintaining cellular balance. But when it becomes unbalanced, the consequences can be critical for health.
Epigenetic Balance: The Fine Line between Protection and Risk
Under normal conditions, DNA methylation maintains the balance between genes that promote cell growth and genes that inhibit it. In the context of cancer, this equilibrium is disrupted: hypermethylation can silence tumor suppressor genes—responsible for slowing abnormal proliferation—while hypomethylation can activate oncogenes that stimulate uncontrolled growth.
These findings have been key in the development of targeted treatments. Drugs such as DNA methyltransferase inhibitors seek to restore healthy methylation patterns and reactivate the protective function of suppressed genes. This therapeutic approach has already demonstrated its potential in various clinical trials.
Lifestyle: A Preventive Tool with Molecular Impact
Beyond pharmacological intervention, science has revealed that factors such as diet, stress, exposure to toxins, and sedentary lifestyle directly influence epigenetic patterns. Therefore, adopting a diet rich in antioxidants and key nutrients, as well as avoiding inflammatory habits, not only protects against chronic diseases but can also reduce the risk of DNA methylation alterations.
In line with this vision, at Sevens we promote a preventative approach through products such as BIO Sevens Turmeric and Omega 3 Sevens , which support cellular balance, combat oxidative stress and could promote healthy genetic expression from a natural and conscious approach.
Conclusion: A New Perspective for the Medicine of the Future
Although DNA methylation is not the only epigenetic mechanism involved in cancer, its study has opened up a revolutionary field in personalized medicine. It provides us not only with new therapeutic tools but also the possibility of preventive interventions. Understanding how our decisions affect genetic expression empowers us to take control of our health, now more than ever, from the very nucleus of our cells.