The key to maintaining young and energetic cells lies not only in creating new mitochondria, but also in knowing how to eliminate those that no longer function properly . This process is known as mitophagy , a specific form of autophagy that selects and recycles damaged mitochondria. Without this internal cleansing capacity, the body accumulates energy waste that generates more free radicals and reduces metabolic efficiency.
Two of the most powerful tools for activating mitophagy naturally are intermittent fasting and regular exercise . Far from being extreme methods, these practices activate evolutionarily conserved pathways that regenerate the cellular energy system, optimize nutrient use, and slow mitochondrial aging .
Intermittent fasting: cellular repair through metabolic rest
During fasting, insulin levels drop, AMPK is activated, and mTOR is suppressed, leading to a cellular environment focused on repair and cleanup rather than growth. In this context, cells initiate mitophagy to remove damaged mitochondria and retain only the most efficient ones.
This process:
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Improves ATP production.
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Decreases oxidative load.
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Reduces the risk of metabolic diseases.
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Improves insulin sensitivity and metabolic flexibility.
Protocols such as 16:8 fasting (16 hours of fasting and 8 hours of eating) are sufficient to activate these benefits without compromising muscle mass or energy.
Physical exercise: the engine of mitochondrial biogenesis
Exercise, especially resistance training, is a direct stimulus for mitochondrial biogenesis and mitophagy. During physical exertion:
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Energy stress is generated that activates PGC-1α , the master molecule of mitochondrial regeneration.
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Less functional mitochondria are removed, leaving room for new, more efficient mitochondria.
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It increases the production of antioxidant enzymes and the cells' ability to handle stress.
In older adults, even regular walking can make a significant difference in mitochondrial renewal and overall vitality.
Strategic support with Sevens products
Using specific supplements can enhance these natural mitochondrial repair and recycling effects:
Omega 3 Sevens (fish oil)
The DHA and EPA in Omega 3 Sevens not only protect mitochondrial membranes, but also enhance the activation of AMPK and the expression of PGC-1α , improving both mitophagy and the creation of new mitochondria.
Turmeric BIO Sevens and Curcumin C3 Reduct Sevens
Both forms of curcumin activate autophagy processes, reduce oxidative stress, and increase the expression of genes involved in mitochondrial renewal . C3 Reduct offers a more potent and sustained effect in cases of high inflammation.
Magnesium Sevens
It supports ATP production during exercise and maintains electrical and enzymatic stability in muscle cells, making it crucial for efficient metabolism during fasting or training.
Sevens Multivitamins
It provides vitamins B, D, E, zinc and selenium: essential nutrients for the energy and antioxidant pathways activated during mitophagy.
Detox Sevens
During the autophagy phase, cellular waste is released and must be efficiently eliminated. Detox Sevens supports the liver in this task, ensuring that the cleansing process is complete.
Conclusion
Fasting and exercise don't just make you feel better: they reactivate the oldest and most effective cellular recycling mechanisms we possess . Thanks to them, the body eliminates inefficient mitochondria and creates new, younger, more functional ones, which translates into more energy, a better metabolism, and less inflammation. With the right support from Sevens products, you can boost this process safely and naturally, building cleaner, more stable, and longer-lasting energy from within.