6.1 – Mitochondrial dysfunction: the energy lost with age – Sevens Nutrition

Mitochondria are vital structures within our cells, known as their "powerhouses." Their primary mission is to generate ATP (adenosine triphosphate) , the molecule that fuels almost all biological processes, from muscle contraction to DNA repair. But in addition to producing energy, mitochondria regulate cell death, genetic signaling, response to oxidative stress, and immune system function.

As we age, these functions become compromised. Mitochondrial dysfunction is a silent but profound phenomenon that occurs when mitochondria cease to function efficiently. This deterioration manifests as decreased energy production, an increase in free radicals, and an increased vulnerability of the body to chronic diseases and cellular aging.

This article is the first in a series of ten posts dedicated to an in-depth exploration of how and why mitochondria fail with age, and what we can do to protect and revitalize them. Using the Sevens approach—based on science, prevention, and functional nutrition—we'll explore how daily habits and strategic supplementation can transform our energetic health.

Index of articles in block 6 – Mitochondrial dysfunction

6.1. Mitochondrial dysfunction: the energy lost with age
6.2. Energy production and mitochondria: the decline of ATP with age
6.3. Mitochondrial oxidative stress: how it affects overall cell health
6.4. Key nutrients for mitochondrial function: CoQ10, magnesium, B vitamins
6.5. Mitochondria and Muscle: How Their Dysfunction Affects Strength and Mobility in Old Age
6.6. The role of omega-3 fatty acids in mitochondrial biogenesis
6.7. Polyphenols as mitochondrial activators: the case of curcumin and resveratrol
6.8. How fasting and exercise stimulate mitochondrial renewal (mitophagy)
6.9. Microbiota and mitochondria: a key dialogue for energy metabolism
6.10. Sevens Strategy for Healthy Mitochondria: Antioxidants, Energy, and Resilience

When mitochondria age, everything slows down.

Mitochondrial dysfunction is characterized by:

Reduction of ATP production.
Increased production of free radicals (ROS) , which damage other cellular structures.
Alterations in cell signaling, which disrupt regeneration cycles.
Activation of inflammatory and degenerative pathways.

Energy-intensive tissues—such as muscles, brain, liver, and heart—are the first to show signs of this deterioration: chronic fatigue, weakness, loss of muscle mass, and cognitive decline . These symptoms, often attributed to natural aging, actually have a deeper and potentially modifiable cause.

Can this process be reversed? Yes, with integrated strategies.

Although mitochondrial damage accumulates over time, it is not irreversible. Several studies have shown that it is possible:

Stimulate mitochondrial biogenesis (create new mitochondria).
Activate mitophagy processes (recycling of damaged mitochondria).
Reducing mitochondrial oxidative stress through key nutrients and lifestyle practices.

How Sevens can help you protect your cellular energy

Sevens Functional Supplements are formulated to support this energy balance from multiple angles:

Magnesium Sevens : essential for ATP production, mitochondrial enzyme activation, and regulation of cellular stress.
Omega 3 Sevens : EPA and DHA fatty acids improve mitochondrial function in key tissues and reduce the inflammation associated with their deterioration.
Sevens Multivitamins : includes B vitamins, selenium and zinc, all of which are essential cofactors for bioenergetic reactions.
BIO Sevens Turmeric : Curcumin activates regeneration pathways such as AMPK and PGC-1α, which stimulate mitochondrial recycling and antioxidant defense.

Conclusion

Mitochondria are at the heart of cellular vitality. When they stop functioning properly, the entire body loses rhythm, efficiency, and resilience . Therefore, understanding mitochondrial dysfunction not only helps us understand aging, but also gives us concrete tools to slow it down. With healthy habits, smart nutrition, and the support of products like Sevens , we can strengthen our mitochondria and prolong the vital drive that sustains everything we do.