Cellular health depends on the efficient production, maintenance, and disposal of proteins. This delicate balance, known as proteostasis , begins to deteriorate with age, promoting the accumulation of misfolded or damaged proteins. However, science has shown that certain essential micronutrients can act as key modulators of proteostasis , supporting everything from protein synthesis to antioxidant and cellular recycling systems.
A diet rich in these nutrients, reinforced with quality supplements, can be an effective preventative tool against accelerated aging and the onset of degenerative diseases.
1. Magnesium: structural stability and metabolic efficiency
Magnesium is an essential mineral in more than 300 enzymatic reactions, many of which regulate protein and energy metabolism. It participates in the translation of RNA into proteins, stabilizes ribosomes, and protects proteins from structural damage induced by free radicals.
Magnesium deficiency, common in older adults, has been associated with increased oxidative stress and protein folding disorders. Magnesium Sevens , formulated for optimal absorption, may be an effective aid in preventing these processes.
2. B vitamins: methylation, protein synthesis and cell repair
Vitamins B6, B12, and folic acid are essential for amino acid synthesis and epigenetic regulation through methylation processes. Their deficiency compromises DNA replication and repair, alters sulfur metabolism, and contributes to the malfunction of structural and enzymatic proteins.
Sevens Multivitamins provides a balanced profile of these vitamins, supporting metabolic functions essential for the production and maintenance of healthy proteins.
3. Zinc: cofactor of antioxidant enzymes and protein stabilizer
Zinc is directly involved in protein synthesis and the function of numerous enzymes, including superoxide dismutase, which protects proteins from oxidative damage. It also plays a structural role, stabilizing protein domains such as zinc fingers, common in gene transcription proteins.
In addition to being included in Sevens Multivitamins , its synergistic action with selenium makes it a pillar in cellular protection against aging.
4. Selenium: antioxidant protection of sensitive proteins
Selenium is essential for the function of enzymes such as glutathione peroxidase, which detoxifies lipid peroxides and protects proteins from oxidation. Selenium deficiency has been observed to correlate with increased protein damage in muscle and brain tissue.
Regularly incorporating it through supplements such as Multivitamin Sevens can improve cellular defense against proteotoxic stress.
5. Omega-3: regulation of inflammation and mitochondrial support
Although they are not micronutrients in the strict sense, the omega-3 fatty acids EPA and DHA are epigenetic modulators that regulate the expression of genes involved in protein metabolism, inflammation, and cellular homeostasis. They help reduce chronic inflammation, which impairs the efficiency of protein recycling systems.
Omega 3 Sevens offers a vegan, purified source of these fatty acids, ideal for those seeking sustainable and effective supplementation.
6. Vitamin D: immunometabolic function and muscle protein synthesis
Vitamin D, through its nuclear receptor (VDR), influences the transcription of genes related to protein synthesis and repair, especially in muscle and bone tissue. Vitamin D deficiency has been linked to sarcopenia, increased inflammation, and decreased regenerative capacity.
The combined use of Vitamin D3 K2 Sevens helps maintain adequate levels of this vitamin, which is key to cellular integrity.
7. Natural antioxidants: polyphenols, carotenoids and bioactive compounds
Plant-derived antioxidants help prevent the oxidation of sensitive proteins. Compounds like curcumin , found in Curcumin Sevens , have demonstrated the ability to modulate pathways such as Nrf2 and mTOR, promoting both antioxidant gene expression and autophagy activation.
8. Iron and copper: delicate balance
Both minerals are necessary for oxygen transport and certain enzymatic functions, but in excess they can induce oxidative damage to proteins. Therefore, it is important to maintain adequate levels and not exceed the recommended doses, especially with non-personalized supplementation.
9. Glutathione and its precursor: N-acetylcysteine (NAC)
Although not yet included in Sevens supplements, NAC has been widely studied for its ability to increase levels of glutathione, the most important intracellular antioxidant. Its positive impact on protein stabilization and protection against oxidative stress is relevant in the context of aging.
10. Nutritional synergies: the comprehensive approach
No nutrient acts in isolation. Maintaining proteostasis depends on a balanced nutritional environment and a synergistic strategy that combines functional nutrition, healthy habits, and evidence-based supplementation.
Conclusion
The loss of proteostasis is one of the most important causes of cellular deterioration with age. Through comprehensive and strategic nutrition, it is possible to support the cellular systems responsible for protein maintenance. The supplements developed by Sevens, formulated with a scientific basis and aligned with a healthy lifestyle, can be key allies in maintaining cellular integrity and promoting active and functional aging.