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7.4 – Adipose tissue and senescence: the silent inflammation of metabolism

7.4 – Tejido adiposo y senescencia: la inflamación silenciosa del metabolismo

When we think of body fat, we often think of it as a simple energy store. But in reality, adipose tissue is an active endocrine organ , regulating hormones, metabolism, inflammation, and immune function. Over the years, this tissue not only accumulates lipids, but also senescent cells , which alter its function and trigger chronic, silent metabolic inflammation.

This process, known as inflammaging , is at the core of multiple chronic diseases associated with aging:

  • Type 2 diabetes

  • Metabolic syndrome

  • Cardiovascular diseases

  • Liver degeneration

In fat tissue, senescent cells release SASPs, promoting insulin resistance, mitochondrial dysfunction, and the spread of damage to other cells. The more visceral the fat, the more inflammatory and senescent it becomes.


The vicious cycle between fat, inflammation and senescence

  1. Excess calories and a sedentary lifestyle promote the enlargement of adipocytes.

  2. These become stressed, enter senescence and release SASP.

  3. SASP activates local immune cells, increasing inflammation.

  4. Inflammation blocks insulin sensitivity and damages new cells.

  5. More fat and more senescent cells accumulate, perpetuating the cycle.

Breaking this cycle requires antioxidant, anti-inflammatory and cleansing action , along with conscious habits such as exercise and a diet rich in fiber, antioxidants and healthy fats.


Support from Sevens products to modulate senescence in adipose tissue

Omega 3 Sevens (fish oil)

It reduces inflammatory mediators derived from senescent adipose tissue. It improves insulin sensitivity and protects the adipocyte membrane from lipid peroxidation.

Organic Turmeric Sevens

It modulates the immune response and acts on fatty tissue as a natural anti-inflammatory. Ideal for maintaining the effect throughout the day and as a therapeutic base for chronic inflammation.

Curcumin C3 Reduce Sevens

Its reduced form of curcumin acts on AMPK and PPARγ, improving the lipid profile, reducing inflammation in adipocytes and promoting the elimination of dysfunctional cells.

Detox Sevens

It facilitates the hepatic elimination of lipophilic toxins accumulated in body fat. It reduces systemic burden and helps purify the cellular environment altered by senescence.

Astaxanthin Sevens

It acts as a shield against oxidative damage caused by excess visceral fat. Its affinity for lipid membranes makes it ideal for protecting lipid-rich tissues.

Magnesium Sevens

It participates in more than 300 metabolic reactions, including glucose and insulin regulation. It supports mitochondrial function in adipose tissue and reduces inflammatory stress.

D3 + K2 Sevens

Both vitamins modulate the immune response in adipose tissue and prevent vascular calcifications related to chronic low-grade inflammation.


Conclusion

Aged fat isn't just an aesthetic issue, but a silent threat to your cellular health. Through a comprehensive approach like the one Sevens offers—focused on regulating metabolism, inflammation, and detoxification—you can transform your fat tissue into a metabolic ally, rejuvenate its environment, and slow down one of the most powerful drivers of systemic aging .