6.4 – Key nutrients for mitochondrial function: CoQ10, magnesium, B vi – Sevens Nutrition

The health of our mitochondria depends largely on the availability of essential nutrients that act as cofactors, stabilizers, and protectors in the complex process of cellular energy production. These nutrients not only enable efficient ATP synthesis, but also protect mitochondria from oxidative damage , facilitate their repair, and stimulate their regeneration.

With aging, the absorption, synthesis, or availability of these nutrients is often compromised , contributing to loss of energy efficiency, chronic fatigue, muscle weakness, and an increased risk of diseases related to mitochondrial impairment.

The most important nutrients to maintain active mitochondria

1. Coenzyme Q10 (CoQ10)

This fat-soluble molecule is essential in the mitochondrial electron transport chain . Its main function is to aid in the production of ATP and act as an intracellular antioxidant , protecting mitochondrial membranes from oxidative damage.

Although Sevens does not currently offer a CoQ10 supplement, its importance as a mitochondrial supplement is widely recognized. Therefore, Sevens has included it in other supplements in its range to support mitochondrial function.

2. Magnesium

Essential for the conversion of nutrients into energy. It directly participates in the reactions that synthesize ATP (ATP requires magnesium to be biologically active). It also regulates the entry of calcium into mitochondria , preventing overloads that can cause dysfunction.

Present in Magnesium Sevens , a high absorption formula that supports cellular bioenergy.

3. B vitamins (B1, B2, B3, B5, B6, B12 and folic acid)

They are key coenzymes in the Krebs cycle and in the production of NAD⁺ and FAD⁺, essential for energy generation. Their deficiency can lead to a functional breakdown of mitochondrial metabolism.

All of these vitamins are included in Sevens Multivitamins , which also provides mineral antioxidants such as zinc and selenium.

4. Omega-3 fatty acids (EPA and DHA)

They are structural components of mitochondrial membranes. They improve membrane fluidity , which facilitates electron transport and energy production. They also reduce inflammation, which damages mitochondria.

Available in Omega 3 Sevens .

5. Polyphenols: curcumin and resveratrol

These compounds activate regeneration pathways such as PGC-1α and AMPK , promoting mitochondrial biogenesis. They also stimulate autophagy and antioxidant defense.

BIO Sevens Turmeric and Curcumin C3 Reduct Sevens contain curcumin in highly bioavailable forms, ideal for aging mitochondria.

6. Organic sulfur and hepatic metabolites

Substances such as sulfur compounds and detoxifying extracts help eliminate mitochondrial toxins and reduce oxidative load.

Detox Sevens combines botanicals that support liver function and intracellular cleansing.

What happens if these nutrients are missing?

Deficiency or dysfunction of these nutrients can lead to:

Insufficient ATP production.
Increased oxidative stress.
Decreased mitochondrial repair capacity.
Activation of degenerative pathways related to cellular aging.

Conclusion

The mitochondria is a sophisticated system that can only function properly if it has the necessary resources . The key nutrients involved in its metabolism and protection aren't optional: they're essential for keeping us energized, mentally clear, and resilient to aging. With the support of Sevens supplements, it's possible to rebuild these building blocks and give our cells back their ability to breathe, repair, and renew themselves .