When we talk about cholesterol or excess weight, we immediately think of diet, exercise, and, in some cases, medication. But there is a silent actor that directly influences these processes: the gut microbiota. Science is showing that bacterial balance in the gut can be a decisive factor in fat metabolism, liver function, and body weight control.

The intestine also regulates your lipids

The liver and gut work closely together. Gut bacteria have the ability to modulate liver enzymes, influence bile acid synthesis, and alter fat absorption. When the gut ecosystem is balanced, lipid metabolism functions more efficiently.

On the contrary, an altered microbiota can contribute to the accumulation of fat in the liver, elevated levels of LDL (the “bad”) cholesterol, and greater difficulty losing weight.

Probiotics that modulate metabolism

Some specific probiotic strains have demonstrated positive effects in this area:

• Reduction of LDL cholesterol and triglycerides in the blood.
• Increased HDL (“good”) cholesterol and improved HDL/LDL ratio.
• Activation of beneficial metabolic pathways such as AMPK and LXR-CYP7A1, which promote the conversion of cholesterol into bile acids for elimination.
• Decreased fat accumulation in the liver.

Studies with strains such as Lactiplantibacillus plantarum J26, T17 and T34 have shown these effects in animal models with high-fat diets, reducing body weight, improving liver markers and normalizing the lipid profile.

Who is this approach useful for?

• People with high cholesterol or mild dyslipidemia.
• People with non-alcoholic fatty liver disease.
• Those looking to lose weight steadily and without rebound effects.
• People who want to protect their cardiovascular health naturally.

Metabolic health from within

The microbiota acts as a silent but powerful regulator of metabolism. And supporting its balance can be an effective, safe, and sustainable strategy for improving clinical markers that have traditionally been treated only externally.

If you're looking for a complementary strategy to support your cholesterol and metabolic health, there are advanced formulas with probiotic strains selected for their action on liver and lipid metabolism. Sevens Nutrition has developed an evidence-backed combination in this field, the Probiotic Complex .